Treatment associated with changes in brain activity in borderline personality disorder

Dr. Mark F. Lenzenweger of Binghamton University and colleagues recently published hopeful findings in regards to the treatment of Borderline Personality Disorder. Investigators took functional magnetic resonance imaging (fMRI) scans of ten women with BPD before and after a 12-month Transference Focused Psychotherapy (TFP) treatment. Results indicate that there is a significant relationship between TFP and cognitive-emotional improvements insomuch that the women’s brain scans showed activation increases in cognitive control areas and activation decreases in areas of emotional reactivity.